
On May 8, 2025, Dr. Kuang published a perspective paper in Science Magazine titled “Replicating a tissue with sound waves.” . Dr. Kuang shares commentary on another Science research paper from Davoodi et al. that achieves ultrasound 3D printing in living animals by developing low-temperature sensitive and biocompatible sono-inks. The researchers also used an imaging-guided process to enhance precision. Kuang says this work improves the technology readiness level for potential translation to applications.
Kuang also identifies future steps needed for this technology. “The fundamental understanding of sound-matter interactions and of the detailed relationship between process conditions, the structure of the printed material, and the resulting properties is needed for more precise manufacturing and better biomaterial design. Additionally, imaging-guided processes and machine learning approaches can play a critical role in procedure precision in a dynamic physiological environment,” he says. “I believe multidisciplinary research and collaboration with doctors and surgeons could push this technique for future clinical minimally invasive surgery and therapy. I hope this technology can finally help human patients to treat many aging-related diseases, such as joint and heart diseases.” (See more)